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Aim: Management of type 1 diabetes in children is a complex process. Active participation of the child and family in diabetes care is essential for achieving good glycaemic control. A good parental understanding of diabetes and its management would be considered a prerequisite for their involvement in the care of their childrens diabetes. The aim of this study was to explore the relationship between parental knowledge of diabetes self management and glycaemic control of ...

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ea0019p7 | Bone | SFEBES2009

A mouse model, Hcalc1, for autosomal dominant hypercalciuria is due to a transient receptor potential cation channel, subfamily V, member 5 (Trpv5) mutation

Loh N , Stechman M , Ahmad B , Hannan F , Hough T , Chiev K-P , Stewart M , Bentley L , Cox R , Brown S , Thakker R

To identify genes causing hypercalciuria, we screened male offspring of C57BL/6J male mice mutagenised by N-ethyl-N-nitrosourea (ENU) for this abnormality. Mice were kept in accordance with UK Home Office welfare guidelines and project licence restrictions. Metabolic cage studies were performed to collect 24-hour urine samples, and this revealed one mouse with hypercalciuria (Hcalc1). Inheritance testing demonstrated that Hcalc1 was inherited as an autosomal domi...

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Endocrine Abstracts

Parental diabetes knowledge and glycaemic control of their children: a questionnaire study

A mouse model, Hcalc1, for autosomal dominant hypercalciuria is due to a transient receptor potential cation channel, subfamily V, member 5 (Trpv5) mutation

BiosciAbstracts